What is carpal tunnel syndrome?
The carpal tunnel is a narrow passage at the wrist formed by bones and ligaments, through which the median nerve and flexor tendons pass. Carpal tunnel syndrome occurs when pressure within this tunnel increases, compressing the median nerve. This leads to sensory symptoms in the thumb, index, middle, and part of the ring finger, and in more advanced cases can cause weakness of the thumb muscles. The condition may occur without an obvious cause or be associated with factors such as repetitive hand use, diabetes, thyroid disease, pregnancy, or inflammatory conditions.
Symptoms and functional impact?
Common symptoms include numbness, tingling, burning, or pain in the hand and fingers, often worse at night and sometimes waking patients from sleep. Some people notice dropping objects, clumsiness, or reduced grip strength. As the condition progresses, symptoms may become constant and muscle wasting at the base of the thumb can occur, indicating ongoing nerve compression. Persistent symptoms can significantly affect work, driving, sleep, and fine motor tasks.
Assessment and diagnosis
Diagnosis is based on a detailed history and physical examination, including assessment of sensation, strength, and characteristic clinical signs. Nerve conduction studies may be used to confirm the diagnosis and assess severity, particularly where symptoms are persistent, atypical, or where surgery is being considered. Accurate assessment is important to distinguish carpal tunnel syndrome from other causes of hand or arm symptoms, such as cervical nerve root compression or peripheral neuropathy.
Treatment options
Initial management may include activity modification and wrist splinting, particularly at night. For patients with persistent or moderate symptoms, corticosteroid injection into the carpal tunnel can provide effective short- to medium-term symptom relief and may delay or avoid the need for surgery in some cases. Injection is also helpful in clarifying diagnosis.
Surgical decompression is recommended for patients with severe symptoms, evidence of nerve damage, or those who do not respond to conservative or injection-based treatment. Repeated injections are not appropriate in cases of ongoing nerve compression or progressive weakness.