Initial management may include activity modification, short-term splinting, and simple analgesia. Corticosteroid injection into the affected tendon sheath has good evidence for symptom relief and is considered first-line treatment for many patients. Injection is often effective after a single treatment, although some patients may require a repeat injection.
Focused shockwave therapy (FSWT) has a limited evidence base in De Quervain’s tenosynovitis and may be considered in selected cases where symptoms persist or where patients wish to avoid injection or surgery. Surgical release of the tendon sheath is reserved for patients with persistent symptoms despite appropriate non-operative treatment.